Cholesterol synthesis is increased in mixed hyperlipidaemia.

doi:10.1016/s0005-2760(98)00103-9

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Article

Cholesterol synthesis is increased in mixed hyperlipidaemia.

Biochimica et biophysica acta - 2 Nov 1998

Naoumova R P, Kim K D, Neuwirth C, Niththyananthan S, Rendell N B, Taylor G W, Thompson G R

Abstract excerpt

We showed previously that hypertriglyceridaemia, but not hypercholesterolaemia, is correlated with increases in cholesterol synthesis and apolipoprotein B secretion in patients with secondary hypertriglyceridaemia. The aim of the present study was to compare the rate of cholesterol synthesis, usi...

Topics

Adult
Apolipoproteins E
Cholesterol
Cholesterol, LDL
Fasting
Female
Humans
Hydroxymethylglutaryl CoA Reductases
Hyperlipidemias
Hyperlipoproteinemia Type II
Male
Mevalonic Acid
Phenotype
Triglycerides

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