Article
Epidermal dendritic cells in psoriasis possess a phenotype associated with antigen presentation: in situ expression of beta 2-integrins.
Journal of the American Academy of Dermatology - 1 Sept 1992
McGregor J M, Barker J N, Ross E L, MacDonald D M
Abstract excerpt
BACKGROUND: Epidermal dendritic cells (DCs) isolated from psoriasis possess greatly enhanced T lymphocyte-activating properties compared with DCs from normal skin, suggesting that DCs in psoriasis express surface antigens crucial for antigen presentation. These include beta 2-integrins and interc...
Topics
- Cell Adhesion Molecules
- Dendritic Cells
- Dermatitis, Atopic
- Epidermis
- Humans
- Immunohistochemistry
- Langerhans Cells
- Lichen Planus
- Lymphocyte Function-Associated Antigen-1
- Phenotype
- Psoriasis
- Receptors, Leukocyte-Adhesion
- Up-Regulation