Dermal dendritic cells are important members of the skin immune system.

Abstract excerpt

In conclusion we have shown that motile cells with a dendritic morphology can be isolated from dermis of normal and diseased human skin. DDC bear high amounts of MHC class II molecules on their surface, and are very potent antigen presenting cells. Subpopulations of these cells acquire certain ultrastructural features of Langerhans cells in-vitro such as Birbeck granule formation and CD1a expression. These newly...

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