Article
Induction of syngeneic cytotoxic T lymphocytes against a B cell tumor. II. Characterization of anti-idiotypic CTL lines and clones.
Cellular immunology - 15 Oct 1992
Chakrabarti D, Ghosh S K
Abstract excerpt
In an earlier communication we showed that idiotypic immunoglobulin (Id+ Ig) of a B cell hybrid, 2C3, can induce cytotoxic T lymphocytes (CTL) in the spleens of mice that are hyperimmunized with the irradiated tumor cells. To understand the extent of heterogeneity in the splenic CTL population, stable anti-idiotypic CTL lines and clones were established from 2C3-primed splenocytes. One representative CTL line...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Surface
- Cell Line
- Clone Cells
- Cytotoxicity, Immunologic
- Immunoglobulin Idiotypes
- Lymphoma, B-Cell
- Mice
- Mice, Inbred BALB C
- Phenotype