Article
Osteoclast precursors circulate in avian blood.
Calcified tissue international - 1 Jul 1992
Alvarez J I, Ross F P, Athanasou N A, Blair H C, Greenfield E M, Teitelbaum S L
Abstract excerpt
The osteoclast is known to be derived from a marrow-residing precursor that is a member of the mononuclear phagocyte family, but the means by which this cell moves from marrow to bone is unknown. We herein demonstrate that mononuclear progenitors capable of differentiating, in vitro, into cells exhibiting the osteoclast phenotype circulate in chickens. The mononuclear fraction was isolated on a density gradient...
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