Article
Retrovirus-mediated gene transfer as an approach to analyze neuroblastoma relapse after autologous bone marrow transplantation.
Human gene therapy - 1 Apr 1992
Rill D R, Buschle M, Foreman N K, Bartholomew C, Moen R C, Santana V M, Ihle J N, Brenner M K
Abstract excerpt
Disseminated neuroblastoma is a malignancy of children often treated by intensive chemotherapy/radiotherapy followed by autologous bone marrow transplantation (ABMT). A high proportion of those treated subsequently relapse. It is unknown if relapse is a consequence of residual disease in the pati...
Topics
- Base Sequence
- Bone Marrow Transplantation
- DNA
- Drug Resistance
- Genetic Markers
- Gentamicins
- Humans
- Molecular Sequence Data
- Neoplasm Recurrence, Local
- Neuroblastoma
- Phenotype
- Polymerase Chain Reaction
- Retroviridae
- Transduction, Genetic
- Transfection
- Transplantation, Autologous