Article
Retrovirus-mediated gene transfer as an approach to analyze neuroblastoma relapse after autologous bone marrow transplantation.
Human gene therapy - 1 Apr 1992
Rill D R, Buschle M, Foreman N K, Bartholomew C, Moen R C, Santana V M, Ihle J N, Brenner M K
Abstract excerpt
Disseminated neuroblastoma is a malignancy of children often treated by intensive chemotherapy/radiotherapy followed by autologous bone marrow transplantation (ABMT). A high proportion of those treated subsequently relapse. It is unknown if relapse is a consequence of residual disease in the patient or of contaminating malignant cells remaining in the infused marrow, which, of necessity, is harvested and stored...
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