Article
XbaI polymorphism in DNA at the apolipoprotein B locus is associated with myocardial infarction (MI).
Clinical genetics - 1 Nov 1993
Bohn M, Bakken A, Erikssen J, Berg K
Abstract excerpt
High levels of low density lipoprotein (LDL) and its apolipoprotein B (apoB) are risk factors for atherosclerosis and myocardial infarction (MI). There is rich genetic polymorphism in apoB, first detected as the Ag allotypes of LDL, but today mostly examined at the DNA level. Genes contribute to...
Topics
- Alleles
- Apolipoproteins B
- Blotting, Southern
- Case-Control Studies
- Chi-Square Distribution
- Cholesterol
- Deoxyribonucleases, Type II Site-Specific
- Female
- Follow-Up Studies
- Gene Frequency
- Genotype
- Humans