Article
DNA polymorphisms of the apolipoprotein B gene (XbaI, EcoRI, and MspI RFLPs) in Norwegians at risk of atherosclerosis and healthy controls.
Acta cardiologica - 1 Aug 1999
Delghandi M, Thangarajah R, Nilsen M, Grimsgaard S, Bønaa K H, Tonstad S, Jørgensen L
Abstract excerpt
OBJECTIVES: Apo B is the exclusive protein constituent of LDL and is ligand on LDL, recognized and bound by the LDL receptor. Several restriction fragment length polymorphisms (RFLPs) of the apo B gene have been shown to be associated with variation in serum lipid levels in different populations. In this study we sought to determine the frequency of XbaI, EcoRI, and MspI polymorphisms and the haplotypes generated...
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