Article
Population-based study of SR-BI genetic variation and lipid profile.
Atherosclerosis - 1 Jul 2004
Morabia Alfredo, Ross Barbara M, Costanza Michael C, Cayanis Eftihia, Flaherty Maria Sol, Alvin Gabriela B, Das Kamna, James Richard, Yang An-Suei, Evagrafov Oleg, Gilliam T Conrad
Abstract excerpt
The variability of the Class B Type I Scavenger Receptor (SR-BI) gene in human populations and the relation of its variants to blood lipids was investigated in a random sample of 1756 untreated adult residents of Geneva, Switzerland, during 1999-2000. A three-step study approach yielded the following results: (1) resequencing the gene's exons and flanking regions in 95 subjects identified four common single...
Topics
- Adult
- Aged
- CD36 Antigens
- Case-Control Studies
- Cholesterol, HDL
- Cholesterol, LDL
- Female
- Gene Frequency
- Genetic Variation
- Genetics, Population
- Humans
- Lipids
- Male
- Middle Aged
