Apo B gene haplotype is associated with lipid profile of higher risk for coronary heart disease in Caucasian Brazilian men.

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Article

Apo B gene haplotype is associated with lipid profile of higher risk for coronary heart disease in Caucasian Brazilian men.

Journal of clinical laboratory analysis - 1 Jan 2001

Machado M O, Hirata M H, Bertolami M C, Hirata R D

Abstract excerpt

We investigated using haplotype analysis whether genetic variation of the apo B gene is associated with a higher risk for coronary heart disease in a Brazilian population. Ins/Del, XbaI, and EcoRI polymorphic sites of the apolipoprotein B (apo B) gene were studied in 67 patients with CHD and in 67 age-matched healthy individuals selected from a population of Brazilians. The allelic frequency of apo B...

Topics

Adult
Aged
Alleles
Apolipoproteins B
Brazil
Cholesterol
Cholesterol, HDL
Coronary Disease
Deoxyribonuclease EcoRI
Deoxyribonucleases, Type II Site-Specific
Female
Gene Deletion
Gene Frequency
Genetic Predisposition to Disease

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Identifiers

PMID: 11170229
PMCID: PMC6875709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Linkage Disequilibrium

Lipids