Article
Hepatitis C virus variants and the role of genotyping.
Journal of hepatology - 1 Jan 1995
Smith D B, Davidson F, Simmonds P
Abstract excerpt
Hepatitis C virus demonstrates considerable divergence in nucleotide sequence. This variation may affect virus detection, disease outcome, and the effectiveness of interferon treatment. For example, infection with genotype 1 is associated with a lower response rate to interferon treatment. Hepati...
Topics
- Enzyme-Linked Immunosorbent Assay
- Genetic Variation
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Serotyping
