Article
Clinical characteristics and antibody profiles of chronic hepatitis C patients: relation to hepatitis C virus genotypes.
Journal of medical virology - 1 Feb 1995
Yuki N, Hayashi N, Mita E, Hagiwara H, Oshita M, Ohkawa K, Katayama K, Kasahara A, Fusamoto H, Kamada T
Abstract excerpt
Genotyping of 179 consecutive Japanese chronic hepatitis C patients was carried out based on the variation in the hepatitis C virus (HCV) core gene. The results were correlated with clinical features and antibody responses toward specific HCV proteins deduced from the nucleotide sequence of genotype I/1a. Genotypes II/1b, III/2a, and IV/2b were identified in 138 (77%), 24 (13%), and 12 (7%) patients,...
Topics
- Adult
- Aged
- Alanine Transaminase
- Amino Acid Sequence
- Base Sequence
- DNA Primers
- Female
- Genotype
- Hepacivirus
- Hepatitis Antibodies
- Hepatitis C
