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Article

Sequence analysis of the hepatitis C virus (HCV) core gene suggests the core protein as an appropriate target for HCV vaccine strategies.

Journal of viral hepatitis - 1 Jan 1995

Hitomi Y, McDonnell W M, Killeen A A, Askari F K

Abstract excerpt

Hepatitis C virus (HCV) is a major healthproblem with a prevalence of 1% in the United States population, and a significant percentage of infected patients progress to chronic liver disease and cirrhosis. Interferon therapy has demonstrated that the immune system can be modulated to alter the acute course of the disease, but long-term treatments remain elusive. Prevention of hepatitis C infection is therefore an...

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PMID: 8745315
DOI: 10.1111/j.1365-2893.1995.tb00035.x

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