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Article

Surface epitope variation via mosaic gene formation is potential key to long-term survival of Trypanosoma brucei.

Molecular and biochemical parasitology - 1 Jul 1992

Kamper S M, Barbet A F

Abstract excerpt

Trypanosoma brucei evades the immune response of its mammalian host by antigenic variation in the major surface antigen (the variable surface glycoprotein or VSG). We examined the generation of diversity in 4 in vivo-derived antigenically related clones of T. brucei by sequencing VSG cDNA from each of the 4 clones and all 5 related genomic copies in the WaTat 1.1 progenitor organism. Each expressed VSG gene was a...

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Identifiers

PMID: 1380125
DOI: 10.1016/0166-6851(92)90004-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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