Article
Isolation and characterization of a lipopolysaccharide mutant of Legionella pneumophila.
FEMS microbiology letters - 15 Jun 1992
Mintz C S, Zou C H
Abstract excerpt
A mutant unable to bind a monoclonal antibody (mAb 1E6) directed against serogroup 1 lipopolysaccharide (LPS) was isolated from L. pneumophila strain Philadelphia-1. SDS-PAGE analysis of isolated LPS from the mutant and wild type revealed that there were no obvious structural differences between the two LPS. The results from Western-blot experiments showed that the mutant LPS was unable to bind mAb 1E6 but...
Topics
- Blood Bactericidal Activity
- Cell Line
- Epitopes
- Humans
- Legionella pneumophila
- Lipopolysaccharides
- Monocytes
- Mutation
- Serotyping