Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of a lipopolysaccharide mutant of Legionella pneumophila.

FEMS microbiology letters - 15 Jun 1992

Mintz C S, Zou C H

Abstract excerpt

A mutant unable to bind a monoclonal antibody (mAb 1E6) directed against serogroup 1 lipopolysaccharide (LPS) was isolated from L. pneumophila strain Philadelphia-1. SDS-PAGE analysis of isolated LPS from the mutant and wild type revealed that there were no obvious structural differences between the two LPS. The results from Western-blot experiments showed that the mutant LPS was unable to bind mAb 1E6 but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Bactericidal Activity
Share to Cell Line
Share to Epitopes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to SDS gene

Share to Lipopolysaccharides

Share to Monocytes

Share to Mutation

Share to Serotyping

Source

Identifiers

PMID: 1379959
DOI: 10.1016/0378-1097(92)90470-9

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of a lipopolysaccharide mutant of Legionella pneumophila.PMID 1379959Read ↗

Characterization of a lipopolysaccharide mutant of Leptospira derived by growth in the presence of an anti-lipopolysaccharide monoclonal antibody.Semantic proximity Read ↗

A structural comparison of lipopolysaccharide biosynthesis loci of Legionella pneumophila serogroup 1 strains.Semantic proximity Read ↗

Random mutagenesis of Legionella pneumophila reveals genes associated with lipopolysaccharide synthesis and recognition by typing monoclonal antibodies.Semantic proximity Read ↗

Isolation and characterization of LPS mutants of Actinobacillus pleuropneumoniae serotype 1.Semantic proximity Read ↗

Cloning and functional characterization of a 30 kb gene locus required for lipopolysaccharide biosynthesis in Legionella pneumophila.Semantic proximity Read ↗

Mutations affecting Leptospira interrogans lipopolysaccharide attenuate virulenceSemantic proximity Read ↗

Lipopolysaccharide engineering in Neisseria meningitidis: structural analysis of different pentaacyl lipid A mutants and comparison of their modified agonist properties.Semantic proximity Read ↗

The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease.Semantic proximity Read ↗

Molecular cloning and characterization of a locus responsible for O acetylation of the O polysaccharide of Legionella pneumophila serogroup 1 lipopolysaccharide.Semantic proximity Read ↗

Vaccine development targeting lipopolysaccharide structure modification.Semantic proximity Read ↗

Moraxella catarrhalis bacterium without endotoxin, a potential vaccine candidate.Semantic proximity Read ↗

Lessons from an LPS-deficient Neisseria meningitidis mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.