Article
A structural comparison of lipopolysaccharide biosynthesis loci of Legionella pneumophila serogroup 1 strains.
BMC microbiology - 4 Sept 2013
Petzold Markus, Thürmer Alexander, Menzel Susan, Mouton Johan W, Heuner Klaus, Lück Christian
Abstract excerpt
BACKGROUND: The lipopolysaccharide (LPS) is the major immuno-dominant antigen of all Legionella species including L. pneumophila. Its diversity is the basis for the classification of L. pneumophila into serogroups and monoclonal subgroups and is thought to be involved in strain specific virulence. The understanding of the genetic basis of the LPS-antigen is incomplete. Thus, we analyzed the genetic locus involved...
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