Article
Antiglobulin testing for CR1-related (Knops/McCoy/Swain-Langley/York) blood group antigens: negative and weak reactions are caused by variable expression of CR1.
Vox sanguinis - 1 Jan 1992
Moulds J M, Moulds J J, Brown M, Atkinson J P
Abstract excerpt
The Knops, McCoy, Swain-Langley and York antigens have recently been identified as being on complement receptor type 1 (CR1, CD35, C3b/C4b receptor). We examined the relationship between CR1 expression and the reactivity of the CR1-related blood group antigens with their specific antibodies. RBC...
Topics
- Alleles
- Antibodies, Monoclonal
- Artifacts
- Blood Group Antigens
- Coombs Test
- Epitopes
- Erythrocyte Membrane
- False Negative Reactions
- Gene Expression
- Humans
- Immunoassay
- Phenotype
- Polymorphism, Restriction Fragment Length
- Receptors, Complement
- Receptors, Complement 3b