Article
Mutational analysis of gap junction formation.
Biophysical journal - 1 Apr 1992
Dahl G, Werner R, Levine E, Rabadan-Diehl C
Abstract excerpt
The paired oocyte cell-cell channel assay was used to investigate the mechanisms involved in the process of formation of gap junction channels. Single oocytes, injected with connexin-specific mRNAs, accumulate a pool of precursors from which cell-cell channels can form rapidly upon pairing. Several lines of evidence, including immunohistochemistry and surface labeling, indicate that part of this precursor pool is...
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