Article
Mutational analysis of gap junction formation.
Biophysical journal - 1 Apr 1992
Dahl G, Werner R, Levine E, Rabadan-Diehl C
Abstract excerpt
The paired oocyte cell-cell channel assay was used to investigate the mechanisms involved in the process of formation of gap junction channels. Single oocytes, injected with connexin-specific mRNAs, accumulate a pool of precursors from which cell-cell channels can form rapidly upon pairing. Sever...
Topics
- Amino Acid Sequence
- Animals
- Biophysical Phenomena
- Biophysics
- Connexins
- Female
- Intercellular Junctions
- Ion Channels
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Oocytes
- Protein Conformation
- Protein Precursors
- RNA, Messenger
- Xenopus laevis