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Article

Functional rescue of defective mutant connexons by pairing with wild-type connexons.

Pflugers Archiv : European journal of physiology - 1 Jan 2001

Hülser D F, Rütz M L, Eckert R, Traub O

Abstract excerpt

We have compared the functional and structural integrity of gap junction channels assembled from a Cx45 truncation mutant with those of gap junction channels assembled from wild-type (wt) Cx45 and Cx43. These channel-forming proteins are constitutively expressed in HeLa cells. The truncation mutant lacks the last 26 amino acids of the COOH-terminus, including nine serine phosphorylation sites that are associated...

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PMID: 11212216
DOI: 10.1007/s004240000460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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