Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic mutations in the VH genes of high-affinity antibodies to self and foreign antigens produced by human CD5+ and CD5- B lymphocytes.

Annals of the New York Academy of Sciences - 4 May 1992

Ikematsu H, Harindranath N, Casali P

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens
Share to Antigens, CD
Share to B-Lymphocyte Subsets
Share to CD5 Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin M

Share to Immunoglobulin Variable Region

Source

Identifiers

PMID: 1376051
DOI: 10.1111/j.1749-6632.1992.tb24631.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic mutations in the VH genes of high-affinity antibodies to self and foreign antigens produced by human CD5+ and CD5- B lymphocytes.PMID 1376051Read ↗

Comparable impact of mutational and selective influences in shaping the expressed repertoire of peripheral IgM+/CD5- and IgM+/CD5+ B cells.Semantic proximity Read ↗

VH genes of human autoantibodies.Semantic proximity Read ↗

Structure of the VH-D-JH segments of human natural polyreactive IgM and IgG antibodies. Use of germline or somatically mutated forms of commonly expressed VH genes.Semantic proximity Read ↗

Structural analysis of the VH-D-JH segments of human polyreactive IgG mAb. Evidence for somatic selection.Semantic proximity Read ↗

Peripheral human CD5+ and CD5- B cells may express somatically mutated VH5- and VH6-encoded IgM receptors.Semantic proximity Read ↗

Molecular evolution of the human immunoglobulin E response: high incidence of shared mutations and clonal relatedness among epsilon VH5 transcripts from three unrelated patients with atopic dermatitis.Semantic proximity Read ↗

Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells.Semantic proximity Read ↗

Anti-MDA5 monoclonal antibodies from patients with dermatomyositis - B cell characteristics and differential targeting of the helicase domainsSemantic proximity Read ↗

Comparison of the human germline and rearranged VH repertoire reveals complementarity between germline variability and somatic mutation.Semantic proximity Read ↗

Single domain antibodies: comparison of camel VH and camelised human VH domainsSemantic proximity Read ↗

Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas.Semantic proximity Read ↗

A sequence analysis of human germline Ig VH and VL genes. The CDR1s of a major proportion of VH, but not VL, genes display a high inherent susceptibility to amino acid replacement.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.