Article
Cobalamin (vitamin B12) repression of the Cob operon in Salmonella typhimurium requires sequences within the leader and the first translated open reading frame.
Molecular microbiology - 1 Mar 1992
Richter-Dahlfors A A, Andersson D I
Abstract excerpt
Expression of the Cob operon in Salmonella typhimurium is repressed by cobalamin (Cbl). Here it is shown that Cbl repression is mediated by a post-transcriptional regulatory mechanism that requires sequences within the leader and the first translated open reading frame, the cbiA gene. Transcriptional and translational Cob::lacZ fusions containing various lengths of Cob DNA were analysed. In a translational...
Topics
- Base Sequence
- Chromosome Deletion
- DNA, Bacterial
- DNA, Recombinant
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Open Reading Frames
- Operon