Article
The cobalamin (coenzyme B12) biosynthetic genes of Escherichia coli.
Journal of bacteriology - 1 Nov 1995
Lawrence J G, Roth J R
Abstract excerpt
The enteric bacterium Escherichia coli synthesizes cobalamin (coenzyme B12) only when provided with the complex intermediate cobinamide. Three cobalamin biosynthetic genes have been cloned from Escherichia coli K-12, and their nucleotide sequences have been determined. The three genes form an operon (cob) under the control of several promoters and are induced by cobinamide, a precursor of cobalamin. The cob...
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