Article
Common senescent cell-specific antibody epitopes on fibronectin in species and cells of varied origin.
Journal of cellular physiology - 1 Mar 1992
Porter M B, Pereira-Smith O M, Smith J R
Abstract excerpt
The phenomenon of in vitro cellular senescence has been demonstrated in cultured cells derived from humans and various other species. We have previously shown that monoclonal antibodies SEN-1, SEN-2, and SEN-3 react to epitopes on fibronectin that are exposed when human diploid fibroblasts become...
Topics
- Animals
- Antibodies
- Breast
- Cells, Cultured
- Cellular Senescence
- Epithelial Cells
- Epithelium
- Epitopes
- Fibronectins
- Humans
- Immunoblotting
- Keratinocytes
- Phenotype