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Article

SOS system induction in Escherichia coli cells with distinct levels of ribonucleotide reductase activity.

Mutation research - 1 Feb 1992

Villaverde A, Barbé J

Abstract excerpt

The UV-mediated induction of recA and sfiA genes in Escherichia coli cells with distinct levels of dATP has been studied. Low levels of dATP were obtained by using either a temperature-sensitive ribonucleotide (RDP) reductase-deficient (nrdA) mutant or a wild-type strain treated with hydroxyurea. High pools of dATP were achieved by using a plasmid overproducing RDP reductase. The results obtained show that...

Topics

Adenosine Triphosphate
Escherichia coli
Gene Expression Regulation, Bacterial
Hydroxyurea
Kinetics
Mutation
Recombinant Fusion Proteins
Ribonucleotide Reductases
SOS Response, Genetics
Temperature
Ultraviolet Rays

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beta-Galactosidase

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Identifiers

PMID: 1370982
DOI: 10.1016/0165-7992(92)90049-n

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1370982-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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