Article
Induction of error-free DNA repair in Escherichia coli by thiamine deprivation.
Mutation research - 1 Feb 1990
Sharma N, Fitt P S
Abstract excerpt
Incubation of Escherichia coli AB1157 in a thiamine-deficient medium causes a large, time-dependent increase in resistance to UV-radiation (254 nm) and a fall in its UV-induced mutation frequency to histidine prototrophy which are abolished in its uvrA mutant, but only delayed in lon- and recA- cells. The response of the lexA3 mutant resembles that of the parental cells. These effects are very similar to those we...
Topics
- Bacterial Proteins
- DNA Repair
- Escherichia coli
- Genes, Bacterial
- Hot Temperature
- Mutation
- SOS Response, Genetics
- Thiamine
- Ultraviolet Rays