Article
Frequency of mutant T lymphocytes defective in the expression of the T-cell antigen receptor gene among radiation-exposed people.
Mutation research - 1 Feb 1992
Kyoizumi S, Umeki S, Akiyama M, Hirai Y, Kusunoki Y, Nakamura N, Endoh K, Konishi J, Sasaki M S, Mori T
Abstract excerpt
The frequency of mutant T lymphocytes defective in T-cell receptor gene (alpha or beta) expression was measured using the 2-color flow cytometric technique. Results for a total of 203 atomic bomb survivors, 78 of whom were proximally exposed (DS86 doses of greater than or equal to 1.5 Gy) and 125...
Topics
- Adult
- Aged
- Female
- Flow Cytometry
- Gene Expression
- Humans
- Iodine Radioisotopes
- Male
- Middle Aged
- Mutation
- Nuclear Warfare
- Receptors, Antigen, T-Cell
