Residues 20, 22, and 26 determine the subtype specificities of staphylococcal enterotoxins C1 and C2.

doi:10.1128/iai.60.2.694-697.1992

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Article

Residues 20, 22, and 26 determine the subtype specificities of staphylococcal enterotoxins C1 and C2.

Infection and immunity - 1 Feb 1992

Turner T N, Smith C L, Bohach G A

Abstract excerpt

Nonconserved residues of staphylococcal enterotoxin C1 (SEC1) were converted to their counterparts in SEC2. The mutants that resulted were examined for reactivity with monoclonal antibodies (MAbs). Substitution at position 20, 22, or 26 interfered with binding of an SEC1-specific MAb. SEC1 mutant...

Topics

Antibodies, Monoclonal
Enterotoxins
Epitopes
Immune Sera
Mutation
Staphylococcus aureus
Structure-Activity Relationship

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