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Article

Predictions of T-cell receptor- and major histocompatibility complex-binding sites on staphylococcal enterotoxin C1.

Infection and immunity - 1 Aug 1994

Hoffmann M L, Jablonski L M, Crum K K, Hackett S P, Chi Y I, Stauffacher C V, Stevens D L, Bohach G A

Abstract excerpt

We have focused on regions of staphylococcal enterotoxin C1 (SEC1) causing immunomodulation. N-terminal deletion mutants lacking residues 6 through 13 induced T-cell proliferation similar to that induced by native toxin. However, mutants with residues deleted between positions 19 and 33, although nonmitogenic themselves, were able to inhibit both SEC1-induced T-cell proliferation and binding of the native toxin...

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Identifiers

PMID: 8039910
DOI: 10.1128/iai.62.8.3396-3407.1994
PMCID: PMC302971

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Source receipt: pubmed, retrieved 7 Sept 2026.

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