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Article

Characterization of the sec1-1 and sec1-11 mutations.

Yeast (Chichester, England) - 1 Dec 2001

Brummer M H, Kivinen K J, Jäntti J, Toikkanen J, Söderlund H, Keränen S

Abstract excerpt

Sec1 proteins are implicated in positive and negative regulation of SNARE complex formation. To better understand the function of Sec1 proteins we have identified the nature of the temperature-sensitive mutations in sec1-1 and sec1-11. The sec1-1 mutation changes a conserved glycine(443) to glutamic acid. The sec1-11 mutation changes a highly conserved arginine(432) to proline. Based on homology and the crystal...

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Identifiers

PMID: 11748729
DOI: 10.1002/yea.796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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