Article
Genetic breeding of L-tyrosine producer from Brevibacterium lactofermentum.
Agricultural and biological chemistry - 1 Mar 1990
Ito H, Sakurai S, Tanaka T, Sato K, Enei H
Abstract excerpt
A wild-type parent of Brevibacterium lactofermentum was converted into an L-Tyr producer by three steps of genetic breeding. First, acquirement of m-fluoro-D, L-phenylalanine resistance (1,000 microgram/ml) brought about MF1317 which produced 3.5 g/l of L-Tyr and a byproduct of 2.8 g/l of L-Phe....
Topics
- 3-Deoxy-7-Phosphoheptulonate Synthase
- Amino Acids
- Brevibacterium
- Drug Resistance, Microbial
- Kinetics
- Mutation
- Phenotype
- Phenylalanine
- Tyrosine