Article
Stability of von Willebrand factor secretion in different human endothelial hybrid cell lines.
Cytotechnology - 1 Jan 1992
Hohenwarter O, Schmatz C, Katinger H
Abstract excerpt
Endothelial cells form a highly differentiated tissue on the inner surface of blood vessels. One of the typical characteristics is the expression of von Willebrand Factor, a protein that participates in blood coagulation. The in vitro cultivation of endothelial cells is limited by the fact that primary cells become senescent after 40 generation doublings. We have immortalized human endothelial cells by somatic...
Topics
- Animals
- Cell Differentiation
- Cell Division
- Cell Line
- Endothelium, Vascular
- Fluorescent Antibody Technique
- Humans
- Hybrid Cells
- Karyotyping
- Mice
- Phenotype
- von Willebrand Factor