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Article

Identification of cultivation-independent markers of human endothelial cell senescence in vitro.

Biogerontology - 1 Aug 2007

Unterluggauer Hermann, Hütter Eveline, Voglauer Regina, Grillari Johannes, Vöth Monika, Bereiter-Hahn Jürgen, Jansen-Dürr Pidder, Jendrach Marina

Abstract excerpt

Human aging processes are regulated by many divergent pathways and on many levels. Thus, to understand such a complex system and define conserved mechanisms of aging, the use of cell culture-based models is a widespread practice. An often stated advantage of in vitro aging of primary cells is the high reproducibility compared to the much more intricate aging of organisms. However, the aging process of cultured...

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PMID: 17377850
DOI: 10.1007/s10522-007-9082-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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