Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Umbilical cord endothelial cells expressing large T antigen: comparison with primary cultures and effect of cell age.

In vitro cellular & developmental biology. Animal - 1 Apr 2000

Fitzgerald U, Hettle S, MacDonald C, McLean J S

Abstract excerpt

A number of human endothelial cell lines from umbilical cord cells (HUVECs) have been generated by transfection with SV40 large T and small t antigen sequences. Comparison of these lines with primary cultures of HUVECs has been carried out by monitoring the expression of a number of endothelial cell markers with specific regard to cell age. The secreted levels of the protein plasminogen activator inhibitor (PAI)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Polyomavirus Transforming
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Interleukin-1

Share to Tissue Plasminogen Activator

Share to Umbilical Cord

Share to Urokinase-Type Plasminogen Activator

Share to von Willebrand Factor

Source

Identifiers

PMID: 10852346
DOI: 10.1290/1071-2690(2000)036<0222:UCECEL>2.0.CO;2

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Umbilical cord endothelial cells expressing large T antigen: comparison with primary cultures and effect of cell age.PMID 10852346Read ↗

Establishment of permanent human endothelial cells achieved by transfection with SV40 large T antigen that retain typical phenotypical and functional characteristics.Semantic proximity Read ↗

Stability of von Willebrand factor secretion in different human endothelial hybrid cell lines.Semantic proximity Read ↗

Human umbilical vein endothelial cells differ from other endothelial cells in failing to express ABO blood group antigens.Semantic proximity Read ↗

Karyotypic and phenotypic changes during in vitro aging of human endothelial cells.Semantic proximity Read ↗

Phenotypic characterization of human umbilical vein endothelial (ECV304) and urinary carcinoma (T24) cells: endothelial versus epithelial features.Semantic proximity Read ↗

The effect of number of days in culture and plasminogen activator inhibitor-1 (PAI-1) 4G/5G genotype on PAI-1 antigen release by cultured human umbilical vein endothelial cells.Semantic proximity Read ↗

Synthesis and secretion of plasminogen activator inhibitor 1 by human endothelial cells in vitro. Effect of active site mutagenized tissue-type plasminogen activator.Semantic proximity Read ↗

Transduced endothelial cells expressing high levels of tissue plasminogen activator have an unaltered phenotype in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.