Article
Trafficking of the microdomain scaffolding protein reggie-1/flotillin-2.
European journal of cell biology - 1 Apr 2008
Langhorst Matthias F, Reuter Alexander, Jaeger Friederike A, Wippich Frank M, Luxenhofer Georg, Plattner Helmut, Stuermer Claudia A O
Abstract excerpt
The reggie/flotillin proteins oligomerize and associate into clusters which form scaffolds for membrane microdomains. Besides their localization at the plasma membrane, the reggies/flotillins reside at various intracellular compartments; however, the trafficking pathways used by reggie-1/flotillin-2 remain unclear. Here, we show that trafficking of reggie-1/flotillin-2 is BFA sensitive and that deletion mutants...
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