Article
Involvement of striatum serotonergic system in the expression of genetically defined catalepsy.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 Jan 2000
Popova N K, Kulikov A V, Avgustinovich D F, Barykina N N
Abstract excerpt
The activity of the rate-limiting enzyme of serotonin biosynthesis, tryptophan hydroxylase, and specific binding of [3H]ketanserin to 5-HT2A receptors and [3H]8-OH-DPAT to 5-HT1A receptors in the striatum of genetically predisposed to catalepsy rats and mice have been studied. The activity of tryptophan hydroxylase in the striatum of rats bred for many generations for predisposition to catalepsy was higher than...
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