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Article

Modulation of the basal ganglia dopaminergic system in a transgenic mouse exhibiting dystonia-like features.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2010

Giannakopoulou Dimitra, Armata Ioanna, Mitsacos Ada, Shashidharan Pullani, Giompres Panagiotis

Abstract excerpt

Dystonia is a movement disorder characterized by involuntary excessive muscle activity and abnormal postures. There are data supporting the hypothesis that basal ganglia dysfunction, and specifically dopaminergic system dysfunction, plays a role in dystonia. In the present study, we used hyperkinetic transgenic mice generated as a model of DYT1 dystonia and compared the basal ganglia dopaminergic system between...

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Identifiers

PMID: 21136125
DOI: 10.1007/s00702-010-0521-5
PMCID: PMC3023171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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