Article
Effect of intercalating dyes on the production of antibiotics by Micromonospora rosaria and Micromonospora purpurea.
Enzyme and microbial technology - 1 Aug 1990
Kim K S, Pai H S, Lee S Y, Ryu D D
Abstract excerpt
The effect of treatment with various intercalating dyes on the ability to produce antibiotics in Micromonospora rosaria and Micromonospora purpurea was studied. Treatment with acriflavine resulted in a high frequency loss of antibiotic productivity in both species. In M. rosaria, the loss of antibiotic-producing ability appeared to be strain-dependent. In M. purpurea, up to 90% of colonies were found to have lost...
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