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Article

Features of regenerated clones with or without fusion treatment between auxotrophic mutants of Streptomyces antibioticus and their antibiotic productivity.

Agricultural and biological chemistry - 1 Nov 1990

Fujimoto Y, Imamura A, Iyeiri C, Shoji S, Kubota Y, Shibata M

Abstract excerpt

During experiments on protoplast fusion of complementary auxotrophic mutants (194 and 11M-21) of Streptomyces antibioticus for strain improvement, the clones (typified by F-40) regenerated on minimal regeneration medium (MRM) were found to be prototrophs, and to produce an antibiotic different from those produced by the parent strain. The protoplast regeneration of each parent was examined as a negative control...

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PMID: 1370035

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