Article
Deciphering the possible role of ctxB7 allele on higher production of cholera toxin by Haitian variant Vibrio cholerae O1.
PLoS neglected tropical diseases - 1 Apr 2020
Naha Arindam, Mandal Rahul Shubhra, Samanta Prosenjit, Saha Rudra Narayan, Shaw Sreeja, Ghosh Amit, Chatterjee Nabendu Sekhar, Dutta Pujarini, Okamoto Keinosuke, Dutta Shanta, Mukhopadhyay Asish Kumar
Abstract excerpt
Cholera continues to be an important public health concern in developing countries where proper hygiene and sanitation are compromised. This severe diarrheal disease is caused by the Gram-negative pathogen Vibrio cholerae belonging to serogroups O1 and O139. Cholera toxin (CT) is the prime virulence factor and is directly responsible for the disease manifestation. The ctxB gene encodes cholera toxin B subunit...
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