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Article

Immunological and virological markers determining progression to AIDS.

The Netherlands journal of medicine - 1 Dec 1994

Schellekens P T, Koot M, Roos M T, Tersmette M, Miedema F

Abstract excerpt

Infection with the human immunodeficiency virus (HIV-1) results in a severe immunodeficiency characterized by a depletion of CD4+ T-helper cells. Furthermore it is well documented that in asymptomatic persons the number of CD4+ cells is also a good predictor of progression to AIDS. However, persons with similar CD4+ cell counts may differ with regard to clinical progression. For this reason the development of...

Topics

Biomarkers
CD4 Lymphocyte Count
Disease Progression
HIV Infections
HIV-1
Humans
Lymphocyte Activation
Phenotype
Predictive Value of Tests
Prognosis
Zidovudine

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PMID: 7838238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7838238-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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