Article
The role of the retinoblastoma gene in breast cancer development.
Cancer treatment and research - 1 Jan 1992
Fung Y K, T'Ang A
Abstract excerpt
The observation that the human retinoblastoma gene is inactivated in about 20% of breast carcinomas indicates that it may be important in the development of these tumors. The fact that the loss of RB1 expression correlates with the progression of the disease, and especially with the inability of...
Topics
- Breast Neoplasms
- Cell Transformation, Neoplastic
- Eye Neoplasms
- Gene Expression Regulation, Neoplastic
- Genes, Retinoblastoma
- Humans
- Mutation
- Neoplasm Metastasis
- Neoplasm Proteins
- Neoplasms, Multiple Primary
- Polymorphism, Restriction Fragment Length
- Retinoblastoma
- Retinoblastoma Protein
- Tumor Cells, Cultured