The retinoblastoma protein and cell cycle regulation.

doi:10.1016/0168-9525(92)90221-o

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Article

The retinoblastoma protein and cell cycle regulation.

Trends in genetics : TIG - 1 May 1992

Hamel P A, Gallie B L, Phillips R A

Abstract excerpt

Although the precise function of the retinoblastoma gene product, p110RB1, remains unknown, recent data suggest that it plays a role in the control of cellular proliferation by regulating transcription of genes required for a cell to enter or stay in a quiescent or G0 state, or for progression through the G1 phase of the cell cycle. However, it is difficult to rationalize the expression of p110RB1 in a wide range...

Topics

Alleles
Animals
Cell Cycle
Cell Division
Cell Transformation, Viral
Child, Preschool
Cyclins
Eye Neoplasms
Fungal Proteins
Genes, Retinoblastoma
Humans
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Models, Genetic

Oncogene Proteins, Viral

Oncogenes

Oncogenic Viruses

Organ Specificity

Source

Open in PubMed

Identifiers

PMID: 1369744
DOI: 10.1016/0168-9525(92)90221-o

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1369744-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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