Article
The retinoblastoma protein and cell cycle regulation.
Trends in genetics : TIG - 1 May 1992
Hamel P A, Gallie B L, Phillips R A
Abstract excerpt
Although the precise function of the retinoblastoma gene product, p110RB1, remains unknown, recent data suggest that it plays a role in the control of cellular proliferation by regulating transcription of genes required for a cell to enter or stay in a quiescent or G0 state, or for progression through the G1 phase of the cell cycle. However, it is difficult to rationalize the expression of p110RB1 in a wide range...
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