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Article

Familial IgA nephropathy: a study of HLA class II allogenotypes in a Chinese kindred.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Nov 1992

Li P K, Burns A P, So A K, Lai K N, Rees A J

Abstract excerpt

We have studied the restriction fragment length polymorphism (RFLP) of the major histocompatibility complex (MHC) class II DQ, DR pattern of a Chinese family with IgA nephropathy (IgAN). The three affected and one apparently unaffected sibling shared the same DR and DQ pattern. The subjects were homozygous for DRw12, DQw7, DQ alpha 1b. The DQw7 allele was further confirmed by polymerase chain reaction (PCR) and...

Topics

Adult
Aged
Alleles
China
DNA Probes
Female
Gene Amplification
Glomerulonephritis, IGA
HLA-DQ Antigens
HLA-DR Antigens
HLA-DR Serological Subtypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1359783
DOI: 10.1016/s0272-6386(12)70257-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1359783-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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