Article
Familial clustering of IgA nephropathy: further evidence in an Italian population.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 May 1999
Scolari F, Amoroso A, Savoldi S, Mazzola G, Prati E, Valzorio B, Viola B F, Nicola B, Movilli E, Sandrini M, Campanini M, Maiorca R
Abstract excerpt
Several lines of evidence suggest that genetic factors have an important role in the pathogenesis of immunoglobulin A (IgA) nephropathy. We report the prevalence of familial IgA nephropathy in a referral center in northern Italy and present the data on HLA genotypes in the families identified. Twenty-six of 185 patients (14%) with IgA nephropathy investigated in Brescia, Italy, were related to at least one other...
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