Drosophila projectin: relatedness to titin and twitchin and correlation with lethal(4) 102 CDa and bent-dominant mutants.

doi:10.1098/rspb.1992.0080

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Drosophila projectin: relatedness to titin and twitchin and correlation with lethal(4) 102 CDa and bent-dominant mutants.

Proceedings. Biological sciences - 22 Jul 1992

Fyrberg C C, Labeit S, Bullard B, Leonard K, Fyrberg E

Abstract excerpt

We have investigated projectin, a large protein of insect muscles, in Drosophila melanogaster. The 5.3 kilobases of coding sequence reported here contains Class I and Class II motifs characteristic of titin and twitchin, arranged in a three domain ... [II-I-I] [II-I-I] ... pattern. Two mutants mapped to the location of the projectin gene in the 102C subdivision of chromosome 4, lethal(4) 102 CDa and...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis elegans Proteins
Calmodulin-Binding Proteins
Cloning, Molecular
Connectin
Drosophila melanogaster
Genes, Dominant
Genes, Lethal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Helminth Proteins

Membrane Proteins

Molecular Sequence Data

Muscle Proteins

Mutation

Protein Kinases

Sequence Homology

Source

Open in PubMed

Identifiers

PMID: 1359548
DOI: 10.1098/rspb.1992.0080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1359548-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila projectin: relatedness to titin and twitchin and correlation with lethal(4) 102 CDa and bent-dominant mutants.PMID 1359548Read ↗

The Drosophila projectin mutant, bentD, has reduced stretch activation and altered indirect flight muscle kinetics.Semantic proximity Read ↗

Role of the elastic protein projectin in stretch activation and work output of Drosophila flight muscles.Semantic proximity Read ↗

Isolation of mutations with dumpy-like phenotypes and of collagen genes in the nematode Pristionchus pacificus.Semantic proximity Read ↗

The coevolution of insect muscle TpnT and TpnI gene isoforms.Semantic proximity Read ↗

D-Titin: a giant protein with dual roles in chromosomes and muscles.Semantic proximity Read ↗

Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes.Semantic proximity Read ↗

The haplolethality paradox of the wupA gene in Drosophila.Semantic proximity Read ↗

Abnormal muscle development in the heldup3 mutant of Drosophila melanogaster is caused by a splicing defect affecting selected troponin I isoforms.Semantic proximity Read ↗

A genetic approach to detect muscle protein interactions in vivo.Semantic proximity Read ↗

In indirect flight muscles Drosophila projectin has a short PEVK domain, and its NH2-terminus is embedded at the Z-band.Semantic proximity Read ↗

Assembly of the giant protein projectin during myofibrillogenesis in Drosophila indirect flight muscles.Semantic proximity Read ↗

Additional sequence complexity in the muscle gene, unc-22, and its encoded protein, twitchin, of Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.