Article
Assembly of the giant protein projectin during myofibrillogenesis in Drosophila indirect flight muscles.
BMC cell biology - 30 Apr 2004
Ayme-Southgate Agnes, Bounaix Christophe, Riebe Theresa E, Southgate Richard
Abstract excerpt
BACKGROUND: Projectin is a giant modular protein of Drosophila muscles and a key component of the elastic connecting filaments (C-filaments), which are involved in stretch activation in insect Indirect Flight Muscles. It is comparable in its structure to titin, which has been implicated as a scaffold during vertebrate myofibrillogenesis. METHODS: We performed immunofluorescence studies on Drosophila pupal tissue...
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