Article
Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism.
The Journal of clinical endocrinology and metabolism - 1 Nov 2004
Tonacchera Massimo, Perri Anna, De Marco Giuseppina, Agretti Patrizia, Banco Maria Elena, Di Cosmo Caterina, Grasso Lucia, Vitti Paolo, Chiovato Luca, Pinchera Aldo
Abstract excerpt
Subclinical hypothyroidism of chronic autoimmune thyroiditis must be distinguished from the rare condition of thyroid resistance to TSH in which variable degrees of congenital insensitivity of the thyroid to a biologically active TSH molecule are present. We studied 42 subjects with slight to moderate elevations of circulating TSH and normal free thyroid hormone levels in whom the diagnosis of autoimmune thyroid...
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