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Article

Phenotypic analysis of hairy cell leukemia: "variant" cases express the interleukin-2 receptor beta chain, but not the alpha chain (CD25).

Blood - 15 Jul 1993

de Totero D, Tazzari P L, Lauria F, Raspadori D, di Celle P F, Carbone A, Gobbi M, Foa R

Abstract excerpt

Hairy cell leukemia (HCL) is a B-cell chronic lymphoproliferative disorder in which the pathologic cells show a strong expression of CD25 (interleukin-2 [IL-2] receptor alpha chain or p55). "Variant" cases of HCL, characterized by hyperleukocytosis, neoplastic elements with a prominent nucleolus...

Topics

Adult
Aged
Antibodies, Monoclonal
B-Lymphocytes
Base Sequence
Cell Membrane
Female
Fluorescent Antibody Technique
Humans
Leukemia, Hairy Cell
Leukemia, Lymphocytic, Chronic, B-Cell
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Molecular Sequence Data

Phenotype

RNA, Messenger

Receptors, Interleukin-2

Source

Identifiers

PMID: 8329708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8329708-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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