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Article

The primary structure of the prion protein influences the distribution of abnormal prion protein in the central nervous system.

The American journal of pathology - 1 Aug 1992

Kitamoto T, Doh-ura K, Muramoto T, Miyazono M, Tateishi J

Abstract excerpt

We immunohistochemically examined tissue sections from patients with prion protein (PrP) polymorphism using hydrolytic autoclaving enhancement. Abnormal PrP accumulations could be classified into plaque formations (plaque-type) and the diffuse gray matter stainings including synaptic structures (synaptic-type). Insertional polymorphism, a point mutation in codon 102 or 117/129, and a polymorphism in codon 129...

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Identifiers

PMID: 1353945
PMCID: PMC1886604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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