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Article

The primary structure of the prion protein influences the distribution of abnormal prion protein in the central nervous system.

The American journal of pathology - 1 Aug 1992

Kitamoto T, Doh-ura K, Muramoto T, Miyazono M, Tateishi J

Abstract excerpt

We immunohistochemically examined tissue sections from patients with prion protein (PrP) polymorphism using hydrolytic autoclaving enhancement. Abnormal PrP accumulations could be classified into plaque formations (plaque-type) and the diffuse gray matter stainings including synaptic structures (...

Topics

Base Sequence
Central Nervous System
Codon
Creutzfeldt-Jakob Syndrome
Dementia
Gerstmann-Straussler-Scheinker Disease
Humans
Immunohistochemistry
Molecular Probes
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

PrPSc Proteins

Prions

Tissue Distribution

Source

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Identifiers

PMID: 1353945
PMCID: PMC1886604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1353945-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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