Article
Human prion diseases with variant prion protein.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Mar 1994
Kitamoto T, Tateishi J
Abstract excerpt
Recent molecular genetic studies revealed that the human prion protein (PrP) gene has a large repertoire of polymorphisms and mutations. Each variant PrP seems to correspond to a distinct type of prion diseases. We report herein that it is useful to classify prion diseases into plaque type or non...
Topics
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- Base Sequence
- Codon
- DNA Primers
- Genetic Variation
- Humans
- Japan
- Middle Aged
- Molecular Sequence Data
- Mutation
- Phenotype
- PrPSc Proteins
- Prion Diseases
- Prions